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Toenail Fungus Treatment - Medical Studies

When treating nail fungus infection we employ ozone to saturate the infected region with oxygen. This has been shown to be an effective method for treating infection and disease in numerous clinical trials. Ozone has very good anti–bacterial characteristics, and ozone oil is used for treating many different types of fungal infection. We also included Manuka oil in our treatment, which is a well-established anti-microbial agent. You can read about some medical studies which have been conducted upon both of these ingredients used in our toenail fungus treatment below:

1: Oxygenated Treatments

Nail Fungus Clinical Treatment Trial at the Policlinico "Pasteur"

Following observations on the clinical efficacy of ozonised oil and its disinfectant properties, a clinical trial was recently conducted at the Policlinico "Pasteur", Cuba. A sample group of 100 nail fungus sufferers was chosen for the trial. The patients were split into two equal-sized groups of 50 in each. One test group was treated using conventional methods, while the other group, was given a topical ozonised oil. The results were as follows:

Of the patients treated with the ozonised oil, 96% made a recovery within 10 to 15 days.

From the group which received the conventional treatment, 20% of the sufferers recovered within 15 days.

See, Ozonized oil and its efficacy in epidermophitosis, De las Cagigas T., Bastard V., Menèndez S.1, Gèmez M.1 and Eng L.1. (Clinic of the family physician from Pasteur Polyclinic, Cuba. National Center for Scientific Research, Cuba.)

Selected quotes about oxygenated treatments:

H2O2 has [...] recently been found to successfully treat a wide variety of human diseases with a minimum of harmful side effects (T. Ramasarma: So M J 1962; 55: 230-32)
Some of the biological killing activity of H202 can be attributed to gamma interferon. Production of gamma interferon by human natural killer cells and monocytes, is stimulated by H202 (Archibald F. S. and M. N. Duong: Infect Immun 1986; 51(2): 631-41)

Bio-oxidatives increase tissue oxygenation, thus bringing about patient improvement (F. Shallenberger: Proceedings: Fourth International Bio-Oxidative Medicine Conference, April 1993)

2: Manuka oil Treatments

Laboratory tests on Manuka oil : A natural anti-microbial

According to Cooke and Cooke (1989), Manuka oil has been shown to be effective in laboratory tests against 39 separate micro-organisms. These include those organisms responsible for toenail fungus, nail fungus & tinea, and they include Trichophyton mentagrophytes and Trichophyton rubrum. Below we provide a list of these micro-organisms with the corresponding Minimum Inhibitory Concentration (MIC) required to treat them. Close to the botton are the organisms which causes nails fungus, toenail fungus and tinea: Trichophyton mentagrophytes and Trichophyton rubrum.

Staphylococcus aureas 0.039
Staphylococcus aureas methacillin resistant 0.0195
Staphylococcus epidermidis 0.078
Streptococcus faecalis 0.039
Streptococcus agalactiae 0.039
Micrococcus luteus 0.0195
Sarcina lutea 0.078
Bacillus subtilis 0.156
Listeria monocytogenes 0.039

Gram Negative Bacteria %

Escherichia coli 2.5
Pseudomonas aeruginosa 997 2.5
Klebsiella pneumoniae 5
Proteus vulgaris 5
Vibrio furnissii 0.625
Pseudomonas aeruginosa 2584 >5
Pseudomonas fluorscens 5

Fungi %

Trichophyton mentagrophytes 0.078
Trichophyton rubrum <0.039
Microsporum canis <0.039
Aspergillus niger >1.25
Candida Albicans 0.625

Cooke A and M. D. Cooke MD, An investigation into the Antimicrobial Properties of Manuka and Kanuka Oil, Cawthron Institute, February 1991